The SkinCeuticals A.G.E. Interrupter Advanced Made Me Put Off Scheduling a Botox Appointment

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skinceuticals review universal


  • Value: 17/20
  • Effectiveness: 20/20
  • Ease of Use: 19/20
  • Aesthetics: 19/20
  • Longevity: 19/20
  • TOTAL: 94/100

I’ve toyed with the idea of getting Botox on and off for the past four or five years but have never pulled the trigger. I’d love to see some improvement in the fine lines that have started to form on my forehead specifically, but I’ve always stopped short of making an appointment because of any combination of the cost, fear and sheer laziness. But with my 32nd birthday quickly approaching (I’m an August Virgo, thank you for asking), I had been considering dipping my toe into the cool waters of injectables more seriously than ever. That is, until I started using the SkinCeuticals A.G.E. Interrupter Advanced anti-wrinkle cream. Here’s what you need to know about this highly effective—if quite costly—product.

What’s in the SkinCeuticals A.G.E. Interrupter Advanced?

This anti-wrinkle cream features 18 percent concentrated proxylane, which helps support skin’s integrity and correct visible signs of aging, 4.25 percent wild fruit flavonoids, which help inhibit glycation (an aging reaction of naturally occurring sugars and dermal proteins) and protect against free radical damage and .1 percent glycyrrhetinic acid, which helps enhance skin’s radiance to counter dull, sallow tone.

How Do You Use the SkinCeuticals A.G.E. Interrupter Advanced?

This updated version of SkinCeuticals’ A.G.E. Interrupter was released in March 2023, and I’ve been using it two to three times a week since. The brand suggests using it twice a day, but considering its hefty price tag—more on that later—I’ve settled for a couple times a week and have still seen results. On nights when I use it, I apply a super thin layer all over my face after cleansing and applying my toner and some sort of oil product (usually the Sunday Riley CEO Glow Vitamin C & Turmeric Face Oil). After about a month, I noticed that some of the fine lines on my forehead that had been bothering me were less defined, and my skin overall feels both smoother and plumper.

And I’m not alone: The product has hundreds of glowing (pun intended) reviews on the SkinCeuticals site. One enthusiastic SkinCeuticals customer raves, “Love this cream! It goes on smooth and is lightweight. It doesn't feel like other creams that seem heavy on your skin. I feel that I have noticed some difference in my fine lines and wrinkles in the short time I've used the cream. I will need to use a bit longer to determine how much of a difference I'm seeing. Will likely purchase again, but use very sparingly as it is very easily blended and a little really does go a long way.”

Are There Any Downsides?

Now onto the negatives. First and foremost, the price. A 1.7-ounce jar of A.G.E. Interrupter Advanced will set you back $185. Woof. While that’s definitely a lot to spend on a skincare product, considering a.) the results and b.) how much bang you get for your buck, I think it’s a bit easier to justify. As I said, I’ve had my jar since March and have barely made a dent into it. It’s also much more affordable than regular Botox injections (according to the American Academy of Dermatology, the average cost of botulinum toxin injections—e.g., Botox®, Dysport®, Xeomin®, Jeuveau®—is $466). Cost aside, I do find that the product feels a bit sticky on my skin, but since I apply it at night before bed, I only notice the slight tackiness for a little while before falling asleep, a small price to pay for rejuvenated skin in the morning.  

Do I still think about getting Botox? I absolutely do, but I’m grateful that this product has postponed the inevitable—in my opinion, for my own face—just a little bit longer.

sarah stiefvater

Wellness Director

Sarah Stiefvater is PureWow's Wellness Director. She's been at PureWow for ten years, and in that time has written and edited stories across all categories, but currently focuses...