Mmmm, the sweet-sour-salty refreshment of a margarita. Not only are local chefs and bartenders mixing up the classic with fresh add-ins like cucumber, pomegranate and jalapeño, they’re swapping tequila for mezcal and even vodka. Intrigued? Here are seven of the most enticing creations that we’ve discovered.

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B.S. Taqueria: Mole Rojo

This new, DTLA upscale taco joint makes a smoky margarita variant that’s a mix of tequila reposado, red-mole grenadine, lime and Ancho Reyes (a liqueur made in Mexico from ancho chiles steeped in sugar-cane spirit) served with a charred chile as garnish. ($12)

514 W. Seventh St.; 213-622-3744 or bstaqueria.com

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Dia de Campo: The Claremont

The cocktail is crisp and refreshing, replacing the traditional tequila and triple sec with cucumber-infused vodka and chartreuse, plus lime and cilantro. ($8)

1238 Hermosa Ave., Hermosa Beach; 310-379-1829 or diadecampohb.com

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The District by Hannah An: Guava Rita

At this new Vietnamese spot, a mix of of Olmeca Altos Blanco, organic guava agave and lime juice, topped by a Kaffir lime tincture, goes down fast and smooth. ($7)

8722 W. Third St.; 310-278-2345 or thedistrictbyha.com

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Gracias Madre: Three Miracles

Smokey mezcal replaces tequila, while lime, mint, sparkling wine and spherical ice cubes frozen with absinthe make this one memorable. ($15)

8905 Melrose Ave.; 323-978-2170 or graciasmadreweho.com

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Mercado: Spicy Cucumber Margarita

The drink is a hit at this lively eatery. Feel the heat with silver tequila, house-made jalapeño purée and a chipotle-salt rim. ($12)

3413 Cahuenga Blvd.; 323-512-2500 or mercadorestaurant.com

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Maradentro: House Margarita

This new Studio City spot’s margarita was inspired by the blue of the ocean. Its salty-sweet flavor comes from Partida Blanco tequila, passion fruit simple syrup and black lava salt. ($12)

11929 Ventura Blvd., Studio City; 818-358-3423 or maradentrorestaurant.com

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Solita Tacos & Margaritas: Frozen Fruit

Cheers vacation-style with a frozen marg from this Baja-style joint: Agavales Blanco blends with triple sec, house-made sweet and sour, orange juice and your choice of fruit purées including pomegranate and watermelon. ($10)

7631 Edinger Ave., Huntington Beach; 714-894-2792 or solitatacos.com

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